I will never have the chance to ride that area of PA, but I did drive around a lot of south central PA a few years ago during an east coast trip, and even being in a cage it was pretty awesome.

 

Find your way to Kinzua Bridge, Woolrich, Bill's Bike Barn, Raystown Lake, Centralia, Port Clinton Hotel..... Any where on Rt 6, Rt 125, Rt 895, Rt 443, Rt.................Not all south but central hahaha.