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Does a 2007 Road King need to be re-mapped when Reinhart slip-on's and a K&N filter is installed?
What is your current set up? Power Commander? FuelPak? Bone Stock?
If you are stock and then add pipes and free flow air cleaner, then I would seriously consider an after market fuel management solution. Do some research on this forum....there are hundreds of threads about this.
Also...click the FuelMoto link above if you want the best solution.