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The rim width will not allow a 200 to fit on a 4.25" rim. A 6" rim is minimum required to run a 190/50 or 190/55 tire on a racebike. The 5.5" rim runs a 180/55 on a sportbike. You are trying to fit a 200 on a rim that is more than an inch narrower. Even if you make it fit, the tire is going to be bulging out on both sides.
I'm pretty sure that 5.5 rim will accept 200 tire
BUT
Can I fit 18x5.5 wheel with 200 tire on a 2010 Heritage Classic without any modification to the bike ?? I do know that it fits Softail Custom & Night train
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