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Grips are very subjective. I ran CoolSAC grips for years. They're a somewhat larger grip with a foam underlay, and a really nice leather outer layer. I was never a fan of wearing gloves, so these worked very well for me. However, they do not work well with all leather gloves. My Gerbing heated leather gloves do not grip well on them which requires a tight grip, which causes fatigue.
I recently switched to the Harley Defiance grips in chrome. They're smaller in diameter and the rubber inserts grip all my leather gloves very well. As such, I now wear gloves all year 'round.
I'd bet the grips that Smitty posted (Harley Get-A-Grip), along with a quality pair of gloves, would do wonders for you.
Ive had a lot of grips over these decades of riding.
The best Ive ever had are a set of leather grips. They have just the right tack. My bare hand sticks to them just enough that I can relax my grip while still holding the throttle on.
with gloves, if the palm has tack (and many dont, in fact many are actually slippery), the same thing applies. I can hold the throttle with no squeeze.
a throttle lock can also help a lot, letting you let go while keeping the throttle open. There are some other devices too, like cramp buster. And even grips with a heel bump.
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