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Not sure what model you have. But I did it myself on my 07 Fatboy. I found the job to be a big pain in the A$$. You have to drain the tank then take off the canopy (cover under the dash with around 10 special screws that have to be replaced.) I wound up dropping parts into the bottom of the tank and had to fish them out...Actually changing the filter is not that bad, but if you have to pull the fuel pump out it gets a bit tricky. Took me a while to figure out how to get it out. The factory hose clamps need to be cut off and replaced. After doing it once, it will be easier next time. If you are good at fixing stuff go for it. It might be easier on some bikes, but mine was a learning experience.
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Did this on my '07 Ultra with the forums post/pics on the subject and it was not bad at all. Did not have to drain the tank but waited until I had less than a gallon left and it was fine. The biggest b^tch was getting the new hose onto the filter because it is really stiff. I ended up buying some new oitker (spelling?) clamps from Napa and using both those and the one you get from the dealer in the kit and it worked just fine. Whole job took me a couple of hours max, but I was being careful and had never done it.
The forum post here on the subject was fantastic and walked you through just about any possible contingency.
Not suggesting that you do this, but I do question the need to change the filter religously at 25,000 miles. Sure, the conditions where you live and the fuel you use plays into it, but I have 80,000 miles on one of my bikes, and 34,000 on the other and neither has had the fuel filter changed.
I'm probably just going to run mine until the time, and if, I have some rideability issue.
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